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Articles (44)
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Reappraisal of p53 mutations in human malignant astrocytic neoplasms by p53 functional assay: Comparison with conventional structural analyses

Mitsuhiro Tada, Richard D. Iggo, Francois Waridel, Michimasa Nozaki, Ryoji Matsumoto, Yutaka Sawamura, Yumiko Shinohe, Jun Ikeda, Hiroshi Abe

Journal:

Molecular Carcinogenesis

Année:

1997

Langue:

english

Fichier:

PDF, 282 KB

english, 1997

Clonality and stability of the p53 gene in human astrocytic tumor cells: Quantitative analysis of p53 gene mutations by yeast functional assay

Mitsuhiro Tada, Richard D. Iggo, Nobuaki Ishii, Yumiko Shinohe, Shirou Sakuma, Anne Estreicher, Yutaka Sawamura, Hiroshi Abe

Journal:

International Journal of Cancer

Année:

1996

Langue:

english

Fichier:

PDF, 437 KB

english, 1996

Prognostic significance of p53 mutation in breast cancer: Frequent detection of non-missense mutations by yeast functional assay

Pierre O. Chappuis, Anne Estreicher, Barbara Dieterich, Hervé Bonnefoi, Michèle Otter, André-Pascal Sappino, Richard Iggo

Journal:

International Journal of Cancer

Année:

1999

Langue:

english

Fichier:

PDF, 123 KB

english, 1999

Clinical significance of p53 functional loss in squamous cell carcinoma of the oropharynx

Atsushi Obata, Masao Eura, Jiichiro Sasaki, Hideyuki Saya, Kazuaki Chikamatsu, Mitsuhiro Tada, Richard D. Iggo, Eiji Yumoto

Journal:

International Journal of Cancer

Année:

2000

Langue:

english

Fichier:

PDF, 277 KB

english, 2000

A Multilateral Mechanistic Study into Asymmetric Transfer Hydrogenation in Water

Xiaofeng Wu, Jianke Liu, Devis Di Tommaso, Jonathan A. Iggo, C. Richard A. Catlow, John Bacsa, Jianliang Xiao

Journal:

Chemistry - A European Journal

Année:

2008

Langue:

english

Fichier:

PDF, 794 KB

english, 2008

Cytotoxic T lymphocyte responses to wild-type and mutant mouse p53 peptides

Sylvie Bertholet, Richard Iggo, Giampietro Corradin

Journal:

European Journal of Immunology

Année:

1997

Langue:

english

Fichier:

PDF, 438 KB

english, 1997

Rare occurrence of inactivating p53 gene mutations in primary non-astrocytic tumors of the central nervous system: reappraisal by yeast functional assay

Michimasa Nozaki, M. Tada, Ryoji Matsumoto, Yutaka Sawamura, Hiroshi Abe, Richard D. Iggo

Journal:

Acta Neuropathologica

Année:

1998

Langue:

english

Fichier:

PDF, 167 KB

english, 1998

p53 mutation in histologically normal mucosa of the aero-digestive tract is not a marker of increased risk for second primary carcinoma in head and neck cancer patients

Anette Escher, Elsa Piotet, Francois Waridel, Richard Iggo, Philippe Monnier

Journal:

European Archives of Oto-Rhino-Laryngology

Année:

2009

Langue:

english

Fichier:

PDF, 208 KB

english, 2009

Significant Correlation of Nitric Oxide Synthase Activity and p53 Gene Mutation in Stage I Lung Adenocarcinoma

Hisao Fujimoto, Ji-ichiro Sasaki, Mitsuhiro Matsumoto, Moritaka Suga, Yukio Ando, Richard Iggo, Mitsuhiro Tada, Hideyuki Saya, Masayuki Ando

Journal:

Cancer Science

Année:

1998

Langue:

english

Fichier:

PDF, 81 KB

english, 1998

Screening patients for heterozygous p53 mutations using a functional assay in yeast

Ishioka, Chikashi, Frebourg, Thierry, Yan, Yu-Xin, Vidal, Marc, Friend, Stephen H., Schmidt, Susanne, Iggo, Richard

Journal:

Nature Genetics

Année:

1993

Fichier:

PDF, 691 KB

1993

Induction of an interferon response by RNAi vectors in mammalian cells

Bridge, Alan J, Pebernard, Stephanie, Ducraux, Annick, Nicoulaz, Anne-Laure, Iggo, Richard

Journal:

Nature Genetics

Année:

2003

Langue:

english

Fichier:

PDF, 581 KB

english, 2003

Retrovirus–mediated p53 gene therapy

Estreicher, Anne, Iggo, Richard

Journal:

Nature Medicine

Année:

1996

Fichier:

PDF, 175 KB

1996

Determining mutational fingerprints at the human p53 locus with a yeast functional assay: a new tool for molecular epidemiology

Inga, Alberto, Iannone, Raffaella, Monti, Paola, Molina, Francesco, Bolognesi, Martino, Abbondandolo, Angelo, Iggo, Richard, Fronza, Gilberto

Journal:

Oncogene

Année:

1997

Langue:

english

Fichier:

PDF, 916 KB

english, 1997

High frequency of p53 mutations in human oral epithelial dysplasia and primary squamous cell carcinoma detected by yeast functional assay

Kashiwazaki, Haruhiko, Tonoki, Hidefumi, Tada, Mitsuhiro, Chiba, Itsuo, Shindoh, Masanobu, Totsuka, Yasunori, Iggo, Richard, Moriuchi, Tetsuya

Journal:

Oncogene

Année:

1997

Langue:

english

Fichier:

PDF, 328 KB

english, 1997

Identification of human p53 mutations with differential effects on the bax and p21 promoters using functional assays in yeast

Flaman, Jean-Michel, Robert, Valérie, Lenglet, Sébastien, Moreau, Viviane, Iggo, Richard, Frebourg, Thierry

Journal:

Oncogene

Année:

1998

Langue:

english

Fichier:

PDF, 378 KB

english, 1998

p53 mutants can often transactivate promoters containing a p21 but not Bax or PIG3 responsive elements

Campomenosi, Paola, Monti, Paola, Aprile, Anna, Abbondandolo, Angelo, Frebourg, Thierry, Gold, Barry, Crook, Tim, Inga, Alberto, Resnick, Michael A, Iggo, Richard

Journal:

Oncogene

Année:

2001

Langue:

english

Fichier:

PDF, 189 KB

english, 2001

Promoter-specific p53-dependent histone acetylation following DNA damage

Kaeser, Matthias D, Iggo, Richard D

Journal:

Oncogene

Année:

2004

Langue:

english

Fichier:

PDF, 295 KB

english, 2004

Nitric oxide as a carcinogen: analysis by yeast functional assay of inactivating p53 mutations induced by nitric oxide

Jun-Ichi Murata, Mitsuhiro Tada, Richard D Iggo, Yutaka Sawamura, Yumiko Shinohe, Hiroshi Abe

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Année:

1997

Langue:

english

Fichier:

PDF, 140 KB

english, 1997

P XII.10 - P XII.10 Trans-dominance analysis of p53 mutants by a yeast functional assay

Gilberto Fronza, Alberto Inga, Sara Cresta, Paola Monti, Anna Aprile, Richard Iggo, Angelo Abbondandolo

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Année:

1997

Langue:

english

Fichier:

PDF, 131 KB

english, 1997

P XI A.10 - P XI A.10 Trans-dominance analysis of p53 mutants by a yeast functional assay

Gilberto Fronza, Alberto Inga, Sara Cresta, Paola Monti, Anna Aprile, Richard Iggo, Angelo Abbondandolo

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Année:

1997

Langue:

english

Fichier:

PDF, 127 KB

english, 1997

Fusion of the BCL9 HD2 domain to E1A increases the cytopathic effect of an oncolytic adenovirus that targets colon cancer cells

Christophe Fuerer, Krisztian Homicsko, Alexander N Lukashev, Anne-Laure Pittet, Richard D Iggo

Journal:

BMC Cancer

Année:

2006

Langue:

english

Fichier:

PDF, 1.18 MB

english, 2006

Determinants of interferon-stimulated gene induction by RNAi vectors

Stephanie Pebernard, Richard D. Iggo

Journal:

Differentiation

Année:

2004

Langue:

english

Fichier:

PDF, 284 KB

english, 2004

Predictive signatures for chemotherapy sensitivity in breast cancer: Are they ready for use in the clinic?

Hervé Bonnefoi, Craig Underhill, Richard Iggo, David Cameron

Journal:

European Journal of Cancer

Année:

2009

Langue:

english

Fichier:

PDF, 396 KB

english, 2009

p53 inactivating mutations in Chinese nasopharyngeal carcinomas

Maria Li Lung, Yazhen Hu, Yue Cheng, Ming Fai Li, Cecilia Man Ching Tang, Sai-ki O, Richard D. Iggo

Journal:

Cancer Letters

Année:

1998

Langue:

english

Fichier:

PDF, 214 KB

english, 1998

New insights into the role of androgen and oestrogen receptors in molecular apocrine breast tumours

Richard D Iggo

Journal:

Breast Cancer Research

Année:

2011

Langue:

english

Fichier:

PDF, 84 KB

english, 2011

Late Expression of Nitroreductase in an Oncolytic Adenovirus Sensitizes Colon Cancer Cells to the Prodrug CB1954

Lukashev, Alexander N., Fuerer, Christophe, Chen, Ming-Jen, Searle, Peter, Iggo, Richard

Journal:

Human Gene Therapy

Année:

2005

Langue:

english

Fichier:

PDF, 571 KB

english, 2005

Structural and spectroscopic studies of rhodium-(I) and -(III) nitrato complexes

Heaton, Brian T., Iggo, Jonathan A., Jacob, Chacko, Blanchard, Helen, Hursthouse, Michael B., Ghatak, Indira, Harman, Mary E., Somerville, Richard G., Heggie, William, Page, Philip R., Villax, Ivan

Journal:

Journal of the Chemical Society Dalton Transactions

Année:

1992

Langue:

english

Fichier:

PDF, 681 KB

english, 1992

Additions and corrections

Heaton, Brian T., Iggo, Jonathan A., Jacob, Chacko, Blanchard, Helen, Hursthouse, Michael B., Ghatak, Indira, Harman, Mary E., Somerville, Richard G., Heggie, William, Page, Philip R., Villax, Ivan, D

Journal:

Journal of the Chemical Society Dalton Transactions

Année:

1992

Langue:

english

Fichier:

PDF, 59 KB

english, 1992

Validation of a yeast functional assay for p53 mutations using clonal sequencing

Iggo, Richard, Rudewicz, Justine, Monceau, Elodie, Sevenet, Nicolas, Bergh, Jonas, Sjoblom, Tobias, Bonnefoi, Hervé

Journal:

The Journal of Pathology

Année:

2013

Langue:

english

Fichier:

PDF, 791 KB

english, 2013

640. Oncolytic Transcriptionally Retargeted Adenovirus Expressing Nitroreductase in Combination with Antiangiogenic Drug RAD001

Lukashev, Alexander N., Homicsko, Krizstian G., Fuerer, Cristophe, Iggo, Richard

Journal:

Molecular Therapy

Année:

2006

Langue:

english

Fichier:

PDF, 83 KB

english, 2006

A rapid PCR fidelity assay

Flaman, Jean-Michel, Frebourg, Thierry, Moreau, Viviane, Charbonnier, Francoise, Martin, Cosette, Ishioka, Chikashi, Friend, Stephen H., Iggo, Richard

Journal:

Nucleic Acids Research

Année:

1994

Langue:

english

Fichier:

PDF, 203 KB

english, 1994

R161: Modèle de greffe orthotopique de cellules humaines dans la glande mammaire de souris immunodéficientes NSG

Richard, E., Schmidt, X., MacGrogan, G., Iggo, R.

Journal:

Bulletin du Cancer

Année:

2010

Langue:

french

Fichier:

PDF, 89 KB

french, 2010

Humanization of the mouse mammary gland by replacement of the luminal layer with genetically-engineered preneoplastic human cells

Verbeke, Stephanie, Richard, Elodie, Monceau, Elodie, Schmidt, Xenia, Rousseau, Benoit, Velasco, Valerie, Bernard, David, Bonnefoi, Herve, MacGrogan, Gaetan, Iggo, Richard D

Journal:

Breast Cancer Research

Année:

2014

Langue:

english

Fichier:

PDF, 4.37 MB

english, 2014

10.1023/a:1008288509498

Iggo, Richard

Journal:

Annals of Oncology

Année:

1998

Langue:

english

Fichier:

PDF, 68 KB

english, 1998

Erratum to: Humanization of the mouse mammary gland by replacement of the luminal layer with genetically engineered preneoplastic human cells

Verbeke, Stephanie, Richard, Elodie, Monceau, Elodie, Schmidt, Xenia, Rousseau, Benoit, Velasco, Valerie, Bernard, David, Bonnefoi, Herve, MacGrogan, Gaetan, Iggo, Richard D

Journal:

Breast Cancer Research

Année:

2015

Langue:

english

Fichier:

PDF, 319 KB

english, 2015

Using the polymerase chain reaction to modify expression plasmids for epitope mapping

Mole, Sara E., Iggo, Richard D., Lane, David P.

Journal:

Nucleic Acids Research

Année:

1989

Langue:

english

Fichier:

PDF, 55 KB

english, 1989

The mammary ducts create a favourable microenvironment for xenografting of luminal and molecular apocrine breast tumours

Richard, Elodie, Grellety, Thomas, Velasco, Valerie, MacGrogan, Gaetan, Bonnefoi, Hervé, Iggo, Richard

Journal:

The Journal of Pathology

Année:

2016

Langue:

english

Fichier:

PDF, 1.38 MB

english, 2016

Evaluation of Methods to Detect p53 Mutations in Ovarian Cancer

Meinhold-Heerlein, Ivo, Ninci, Elena, Ikenberg, Hans, Brandstetter, Thomas, Ihling, Christian, Schwenk, Ildiko, Straub, Alexander, Schmitt, Beate, Bettendorf, Herta, Iggo, Richard, Bauknecht, Thomas

Journal:

Oncology

Année:

2001

Langue:

english

Fichier:

PDF, 301 KB

english, 2001

The ninth ENBDC Weggis meeting: growth and in-depth characterisation of normal and neoplastic breast cells

Wiese, Katrin E., Amante, Romain J., Vivanco, Maria dM., Bentires-Alj, Mohamed, Iggo, Richard D.

Journal:

Breast Cancer Research

Année:

2017

Langue:

english

Fichier:

PDF, 280 KB

english, 2017

MICADo – Looking for Mutations in Targeted PacBio Cancer Data: An Alignment-Free Method

Rudewicz, Justine, Soueidan, Hayssam, Uricaru, Raluca, Bonnefoi, Hervé, Iggo, Richard, Bergh, Jonas, Nikolski, Macha

Journal:

Frontiers in Genetics

Année:

2016

Langue:

english

Fichier:

PDF, 1.78 MB

english, 2016

Polyanionic Ligand Platforms for Methyl- and Dimethylaluminum Arrays

Richards, Philip I., Lawson, Gavin T., Bickley, Jamie F., Robertson, Craig M., Iggo, Jonathan A., Steiner, Alexander

Journal:

Inorganic Chemistry

Année:

2019

Fichier:

PDF, 2.28 MB

2019

Polyanionic Ligand Platforms for Methyl- and Dimethylaluminum Arrays

Richards, Philip I., Lawson, Gavin T., Bickley, Jamie F., Robertson, Craig M., Iggo, Jonathan A., Steiner, Alexander

Journal:

Inorganic Chemistry

Année:

2019

Langue:

english

Fichier:

PDF, 2.28 MB

english, 2019

Molecular apocrine tumours in EORTC 10994/BIG 1-00 phase III study: pathological response after neoadjuvant chemotherapy and clinical outcomes

Bonnefoi, Hervé, MacGrogan, Gaetan, Poncet, Coralie, Iggo, Richard, Pommeret, Fanny, Grellety, Thomas, Larsimont, Denis, Bécette, Véronique, Kerdraon, Olivier, Bibeau, Frédéric, Ghnassia, Jean-Pierre,

Journal:

British Journal of Cancer

Année:

2019

Langue:

english

Fichier:

PDF, 514 KB

english, 2019

A genomeâscale CRISPR knockâout screen in chronic myeloid leukemia identifies novel drug resistance mechanisms along with intrinsic apoptosis and MAPK signaling

Lewis, Matthieu, ProuzetâMaulÃ©on, ValÃ©rie, Lichou, Florence, Richard, Elodie, Iggo, Richard, Turcq, BÃ©atrice, Mahon, FranÃ§oisâXavier

Journal:

Cancer Medicine

Année:

2020

Fichier:

PDF, 1018 KB

2020